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Oncogene - Wikipedia
An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated or expressed at high levels.. Most normal cells will undergo a programmed form of rapid cell death when critical functions are altered and malfunctioning.Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead.

Oncogene | biology | Britannica.com
Oncogene: Oncogene, genetic material that carries the ability to induce cancer. An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been altered or mutated from its original form, the proto-oncogene. Operating as a positive growth regulator, the proto-oncogene is involved in promoting the

RET proto-oncogene - Wikipedia
The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular signalling molecules. RET loss of function mutations are associated with the development of Hirschsprung's disease, [citation needed] while gain of function mutations are associated with the development of various types of human cancer ...

OMIM Entry - * 602533 - ONCOGENE DJ1; DJ1
DJ1, or PARK7, has pleiotropic function that includes roles as a chaperone with protease activity, a transcriptional regulator, and an antioxidant scavenger and redox sensor. DJ1 is also involved in tumorigenesis and in maintaining mitochondrial homeostasis (summary by Ottolini et al., 2013 ...

Oncogene - Wikipedia
Un oncogene è un gene, o una serie di nucleotidi che codificano una proteina, che potenzialmente indirizzano la cellula verso lo sviluppo di un fenotipo neoplastico.Solitamente gli oncogeni intervengono nello sviluppo tumorale e aumentano le possibilità che lo sviluppo (proliferazione e differenziamento) di una cellula si diriga in senso tumorale.

The Her2 Neu (Erbb2) Oncogene In Breast Cancer -Dr Lal ...
An understanding of breast cancer, along with numerous studies that have been performed to identify prognostic and predictive factors in the treatments.

oncogene nell'Enciclopedia Treccani
oncogene In biologia, gene che può potenzialmente indurre trasformazione neoplastica nelle cellule che lo contengono o nelle cellule dove viene introdotto ( tumore).. Alcuni retrovirus, implicati in molti tumori animali ma in pochi tumori umani, in aggiunta o in sostituzione dei propri geni normali, contengono un o. che non è necessario ai virus stessi ma è in grado di trasformare le ...

UpToDate
INTRODUCTION — A group of patients with non-small cell lung cancer (NSCLC) have tumors that contain an inversion in chromosome 2 that juxtaposes the 5' end of the echinoderm microtubule-associated protein-like 4 (EML4) gene with the 3' end of the anaplastic lymphoma kinase (ALK) gene, resulting in the novel fusion oncogene EML4-ALK [].This fusion oncogene rearrangement is transforming both ...

Onkogen – Wikipedia
Onkogene (wörtlich Krebs-Gene) sind Teile des Erbgutes einer Zelle, die im Falle ihrer übermäßigen Aktivierung den Übergang vom normalen Wachstumsverhalten der Zelle zu ungebremstem Tumorwachstum fördern. Das „gen“ in Onkogen wird hier nicht, wie in den Worten karzinogen oder mutagen, im Sinne von „erzeugend“ oder „fördernd“ benutzt, sondern leitet sich direkt von dem Wort ...

ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1; ABL1 - OMIM
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response.

 

 

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