Oncogene - Wikipedia
An oncogene is a gene that has the potential to cause cancer. In tumor cells, they are often mutated and/or expressed at high levels. Most normal cells will undergo a programmed form of rapid cell death when critical functions are altered and malfunctioning. Activated ...
Oncogene | biology | Britannica.com
Oncogene: Oncogene, genetic material that carries the ability to induce cancer. An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been altered or mutated from its original form, the proto-oncogene. Operating as a positive growth regulator, the proto-oncogene is involved in promoting the
Oncogene | definition of oncogene by Medical dictionary
oncogene [ong´ko-jēn] a gene found in the chromosomes of tumor cells whose activation is associated with the initial and continuing conversion of normal cells into cancer cells. on·co·gene (ong'kō-jēn), 1. Any of a family of genes that normally encodes proteins that are involved in cell growth or regulation (e.g., protein kinases, GTPases, nuclear ...
How Oncogenes Cause Cancer - NDSU
The change of an oncogene from normal to cancerous function can be caused by a simple point mutation in the sequence of a gene. For example, a change in the ras oncogene, located on human chromosome 11, from guanine to cytosine is frequently associated with bladder cancer. This simple change results ...
Oncogenes - The Cell - NCBI Bookshelf
Many other oncogenes differ from the corresponding proto-oncogenes by point mutations, resulting in single amino acid substitutions in the oncogene products. In some cases, such amino acid substitutions (like the deletions already discussed) lead to unregulated activity of the oncogene proteins.
Oncogene | Definition of Oncogene by Merriam-Webster
Oncogene definition is - a gene having the potential to cause a normal cell to become cancerous. a gene having the potential to cause a normal cell to become cancerous… See the full definition See the full definition
Oncogene Flashcards | Quizlet
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Oncogene - an overview | ScienceDirect Topics
Oncogene An oncogene is defined as a gene that encodes a protein that is capable of transforming cells in culture or inducing cancer in animals. From: Comprehensive Toxicology, 2010
Oncogene - Journals - NCBI
Oncogene journal page at PubMed Journals. Published by Nature Publishing Group
What are Oncogenes? - News Medical
An example of an oncogene in this class is c-Sis. Receptor tyrosine kinases – Examples of oncogenes in this class include the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), vascular endothelial growth factor receptor (VEGFR) and human epidermal growth factor receptor 2 (HER2/neu). The proteins ...